BIMAL PHARMA PVT. LTD.
www.bimalpha.com

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ASPARTAME

BP
/ EP / FCC V / USP’31

1

NOMENCLATURE

Aspartyl
Phenylalinine Methyl Ester (APM)

N-L-Alpha-Aspartyl-Phenylalanine,
1-Methyl Ester.

L-Aspartyl-L-Phenylalanine
Methyl Ester.

(3S)-3-amino-4-[[(1S)-1-benzyl-2-methoxy-
2- oxoethyl]amino]-4-oxobutanoic acid.

2

CAS
NO.

22839-47-0
/
53906-69-7
/ 7421-84-3

3

MELTING POINT

248°C  to
250°C

4

EMPIRICAL
FORMULA

C14H18N2O5

5

MOL.
WT.

294.31

6

STRUCTURAL FORMULA

7

DESCRIPTION

White,
Odorless, crystalline Powder, having a strong sweet taste
.

8

SOLUBILITY

Sparingly
soluble or slightly soluble in Water
and in Alcohol.

Practically
insoluble in Hexane and in Methylene
Chloride.

9

IDENTIFICATION

A) By UV

B) By IR

C) By TLC

D) By Color Development.

10

CLARITY & COLOR
OF  SOLUTION

(Appearance
of Solution)

0.8 gm., is soluble in 100 ml. water
the
solution is Clear and not more  intensely
colored than Ref. Solution GY 6

11

SPECIFIC ROTATION

+14.5°
to +16.5°

12

TRANSMITTANCE

NLT 95.0%

13

DIKETOPIPERZINE  (DKP)

Less than 1.5 %

14

OTHER
IMPURITIES

(OTHER
RELATED SUBSTANCES)

NMT 2%

15

HEAVY METALS

NMT 0.001 % (10 ppm) .

16

ORGANIC
VOLATILE  IMPURITIES

Pass the Test (as per USP).

17

ARSENIC

NMT 3 ppm
(As per USP)

18

LOSS ON DRYING

NMT 4.5%

19

RESIDUE ON
IGNITION       (Sulphated
Ash)

NMT
0.2%

20

pH

4.5 – 6.0

21

ASSAY (ODB)

98.0%
to 102.0%

22

PACKING

10
Kgs. / 20 Kgs. Fibre drums with double
PE liners.

1
Kg. packing on special request, in original
intact packing.

23

AVAILABLE GRADES

Regular Powder (80% passing through 100
Mesh)

Regular
Granular (Particle Size, 20 – 60 Mesh)

High Density Powder (HD
Powder)
(Particle Size, 100 – 200 Mesh)

Fine
Granular (Particle Size, 60 – 100 Mesh)

Super
Fine Powder
(Passing
through 300 Mesh)

24

APPLICATIONS

Sweetening
Agent.

Used
in Fields of Nutrition , Medicines and Cosmetics.